S100A8 / S100A9（MRP（8/14）是一種鈣結合蛋白，由中性粒細胞和單核細胞分泌而成，糞便中S100A8 / S100A9是贅生性和炎癥性胃腸疾病的標志物，一般情況下很難區分腸易激綜合癥和慢性炎癥性腸病，所以很多時候會導致廣泛和不必要結腸鏡檢查，而S100A8 / S100A9檢測可以使兩組患者明確區分。將該標記物與結腸直腸癌的標準糞便潛血篩查進行比較，能夠清楚地證明了糞便S100A8 / S100A9測試的診斷優勢，該參數具有較高的診斷價值：如果糞便中的S100A8 / S100A9水平較低，則很可能不存在器質性疾病。

Immundiagnostik（IDK）公司能提供大/小鼠鈣結合蛋白S100A8/S100A9檢測試劑盒（酶聯免疫法） ，用于定量大/小鼠糞便、血清、尿液、組織提取液及細胞培養上清液中的S100A8/S100A9(鈣衛蛋白MRP8/14 )。

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